Gene Information
Gene NameSRXN1
OrganismHomo sapiens (Human)
Gene Length137
Protein NamesSulfiredoxin-1 (EC 1.8.98.2)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000271303 )
Evolutionary StageEukaryota
AlphaFoldDBQ9BYN0
Gene CardSRXN1
Uniprot IDQ9BYN0
PfamPF02195
In ASDno
Allosteric Predictionno (-0.677445114)
Ortholog in AnimalsAlpaca_ SRXN1 ( ortholog_one2one )
Dog_ SRXN1 ( ortholog_one2one )
GuineaPig_ SRXN1 ( ortholog_one2one )
Macaque_ SRXN1 ( ortholog_one2one )
Mouse_ Srxn1 ( ortholog_one2one )
Pig_ SRXN1 ( ortholog_one2one )
Rabbit_ SRXN1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed with highest levels in kidney, lung, spleen and thymus. {ECO:0000269|PubMed:15448164}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);0.001445(Rat);0.017391(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1XW3  (X-ray  1.65A  1XW4  (X-ray  2.00A  1YZS  (NMR  2B6F  (NMR  2RII  (X-ray  2.60A  3CYI  (X-ray  1.80A  3HY2  (X-ray  2.10A  7LJ1  (X-ray  2.97A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:15448164}.
Mouse PG classificationNA
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