Gene Information
Gene NameHSDL2
OrganismHomo sapiens (Human)
Gene Length418
Protein NamesHydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) (Short chain dehydrogenase/reductase family 13C member 1)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000119471 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ6YN16
Gene CardHSDL2
Uniprot IDQ6YN16
PfamPF00106; PF02036
In ASDno
Allosteric Predictionno (-0.932287097)
Ortholog in AnimalsAlpaca_ HSDL2 ( ortholog_one2one )
Dog_ HSDL2 ( ortholog_one2one )
GuineaPig_ HSDL2 ( ortholog_one2one )
Macaque_ HSDL2 ( ortholog_one2one )
Mouse_ Hsdl2 ( ortholog_one2one )
Pig_ HSDL2 ( ortholog_one2one )
Rat_ Hsdl2 ( ortholog_one2one )
Rabbit_ HSDL2 ( ortholog_one2one )
OhnologsNA
ParalogsDHRS7C, DHRS7, HSD11B1, RDH8, CBR3, DHRS7B, DHRS2, HSD11B1L, DHRS4L2, DHRS4, DHRS11, CBR1, DHRS1
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:12834046}.
Pharmacological Animal Models0.009354(Chimpanzee);0.001000(Mouse);0.001990(Rat);0.033333(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3KVO  (X-ray  2.25A 
DBSNP NA 
Subcellular location [CC]Peroxisome {ECO:0000269|PubMed:19703561}.
Mouse PG classificationNA
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