| Gene Information | |
|---|---|
| Gene Name | HSDL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 330 |
| Protein Names | Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000103160 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q3SXM5 |
| Gene Card | HSDL1 |
| Uniprot ID | Q3SXM5 |
| Pfam | PF00106 |
| In ASD | no |
| Allosteric Prediction | no (-1.192353872) |
| Ortholog in Animals | Alpaca_ HSDL1 ( ortholog_one2one ) Dog_ HSDL1 ( ortholog_one2one ) Macaque_ HSDL1 ( ortholog_one2one ) Mouse_ Hsdl1 ( ortholog_one2one ) Pig_ HSDL1 ( ortholog_one2one ) Rat_ Hsdl1 ( ortholog_one2one ) Rabbit_ HSDL1 ( ortholog_one2one ) |
| Ohnologs | HSD17B12 |
| Paralogs | SDR9C7, HSD17B14, HSD17B7, HSD11B2, DHRS12, RDH12, HSD17B4, DHRS9, RDH11, RDH16, HSD17B8, HSD17B11, BDH1, WWOX, HSD17B2, RDH5, DHRS3, HSD17B13, HSD17B12, SDR16C5, HSD17B1, RDH10, HSD17B10, HSD17B3, HSD17B6 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. {ECO:0000269|PubMed:12153137, ECO:0000269|PubMed:19026618}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11540436 rs4378600 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:19026618}. |
| Mouse PG classification | NA |
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