| Gene Information | |
|---|---|
| Gene Name | HSDB3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II) (3-beta-HSD II) (3-beta-HSD adrenal and gonadal type) [Includes: 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid Delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P26439 |
| Gene Card | HSD3B2 |
| Uniprot ID | P26439 |
| Pfam | PF01073 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in adrenal gland, testis and ovary. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28934880 rs28934880 rs4986954 rs757033996 rs6211 rs1388517943 rs587628683 rs80358219 rs779418168 rs35486059 rs762479018 rs759422374 rs765547422 rs80358220 rs35887327 rs1399005702 rs1411029929 rs80358221 rs121964897 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:25322271}; Single-pass membrane protein {ECO:0000255}. Mitochondrion membrane; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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