Gene Information
Gene NameGTF2H4
OrganismHomo sapiens (Human)
Gene Length462
Protein NamesGeneral transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000213780 )
3 ( ENSG00000221974 )
3 ( ENSG00000226384 )
3 ( ENSG00000233149 )
3 ( ENSG00000234370 )
3 ( ENSG00000236895 )
Evolutionary StageEukaryota
AlphaFoldDBQ92759
Gene CardGTF2H4
Uniprot IDQ92759
PfamPF03849; PF18307
In ASDno
Allosteric Predictionno (-0.238261772)
Ortholog in AnimalsAlpaca_ GTF2H4 ( ortholog_one2one )
Dog_ GTF2H4 ( ortholog_one2one )
GuineaPig_ GTF2H4 ( ortholog_one2one )
Macaque_ GTF2H4 ( ortholog_one2one )
Mouse_ Gtf2h4 ( ortholog_one2one )
Pig_ GTF2H4 ( ortholog_one2one )
Rabbit_ GTF2H4 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5IVW  (EM  10.00A  5IY6  (EM  7.20A  5IY7  (EM  8.60A  5IY8  (EM  7.90A  5IY9  (EM  6.30A  5OF4  (EM  4.40A  6NMI  (EM  3.70A  6O9L  (EM  7.20A  6O9M  (EM  4.40A  6RO4  (EM  3.50A  7AD8  (EM  3.50A  7EGB  (EM  3.30A  7EGC  (EM  3.90A  7ENA  (EM  4.07A  7ENC  (EM  4.13A  7LBM  (EM  4.80A  7NVR  (EM  4.50A  7NVV  (EM  2.90A  7NVW  (EM  4.30A  7NVX  (EM  3.90A  7NVY  (EM  7.30A  7NVZ  (EM  7.20A  7NW0  (EM  6.60A 
DBSNP rs3218820 
Subcellular location [CC]Nucleus.
Mouse PG classificationNA
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