| Gene Information | |
|---|---|
| Gene Name | TUT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 874 |
| Protein Names | Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000149016 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H6E5 |
| Gene Card | TUT1 |
| Uniprot ID | Q9H6E5 |
| Pfam | PF03828; PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-1.240291341) |
| Ortholog in Animals | Alpaca_ TUT1 ( ortholog_one2one ) Dog_ TUT1 ( ortholog_one2one ) GuineaPig_ TUT1 ( ortholog_one2one ) Macaque_ TUT1 ( ortholog_one2one ) Mouse_ Tut1 ( ortholog_one2one ) Pig_ TUT1 ( ortholog_one2one ) Rat_ Tut1 ( ortholog_one2one ) Rabbit_ TUT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TUT4, TENT2, MTPAP, TUT7 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:18288197}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E5G (NMR - ) 5WU1 (X-ray 2.80A ) 5WU2 (X-ray 2.95A ) 5WU3 (X-ray 2.70A ) 5WU4 (X-ray 2.80A ) 5WU5 (X-ray 3.40A ) 5WU6 (X-ray 3.21A ) |
| DBSNP | rs3197865 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:16790842}. Nucleus speckle {ECO:0000269|PubMed:18288197, ECO:0000269|PubMed:18305108}. |
| Mouse PG classification | NA |
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