| Gene Information | |
|---|---|
| Gene Name | ORMDL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | ORM1-like protein 1 (Adoplin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000128699 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P0S3 |
| Gene Card | ORMDL1 |
| Uniprot ID | Q9P0S3 |
| Pfam | PF04061 |
| In ASD | no |
| Allosteric Prediction | no (-1.259636296) |
| Ortholog in Animals | Alpaca_ ORMDL1 ( ortholog_one2one ) Dog_ ORMDL1 ( ortholog_one2one ) GuineaPig_ ORMDL1 ( ortholog_one2one ) Macaque_ ORMDL1 ( ortholog_one2one ) Mouse_ Ormdl1 ( ortholog_one2one ) Pig_ ORMDL1 ( ortholog_one2one ) |
| Ohnologs | ORMDL2, ORMDL3 |
| Paralogs | ORMDL2, ORMDL3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. Expressed at intermediate level in pancreas, placenta and brain but low in skeletal muscle and lung. {ECO:0000269|PubMed:12093374}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374}. |
| Mouse PG classification | NA |
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