| Gene Information | |
|---|---|
| Gene Name | SHARP |
| Organism | Homo sapiens (Human) |
| Gene Length | 3664 |
| Protein Names | Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | SPEN |
| Uniprot ID | Q96T58 |
| Pfam | PF00076; PF07744 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at high level in brain, testis, spleen and thymus. Expressed at intermediate level in kidney, liver, mammary gland and skin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1OW1 (X-ray 1.80A ) 2RT5 (NMR - ) 4P6Q (X-ray 2.00A ) |
| DBSNP | rs848208 rs848209 rs12095818 rs848210 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11331609}. Note=Associates with chromatin. |
| Mouse PG classification | NA |
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