| Gene Information | |
|---|---|
| Gene Name | HS3ST2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 367 |
| Protein Names | Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000122254 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y278 |
| Gene Card | HS3ST2 |
| Uniprot ID | Q9Y278 |
| Pfam | PF00685 |
| In ASD | no |
| Allosteric Prediction | no (-1.315417948) |
| Ortholog in Animals | Alpaca_ HS3ST2 ( ortholog_one2one ) GuineaPig_ HS3ST2 ( ortholog_one2one ) Macaque_ HS3ST2 ( ortholog_one2one ) Mouse_ Hs3st2 ( ortholog_one2one ) Pig_ HS3ST2 ( ortholog_one2one ) Rat_ Hs3st2 ( ortholog_one2one ) Rabbit_ HS3ST2 ( ortholog_one2one ) |
| Ohnologs | HS3ST3B1, HS3ST3A1 |
| Paralogs | HS3ST3A1, NDST1, HS3ST1, HS3ST4, NDST3, HS3ST6, NDST4, NDST2, HS3ST3B1, HS3ST5 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart, placenta, lung and skeletal muscle. {ECO:0000269|PubMed:9988767}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17725080 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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