Gene Information
Gene NameHRSP12
OrganismHomo sapiens (Human)
Gene Length137
Protein Names2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP52758
Gene CardRIDA
Uniprot IDP52758
PfamPF01042
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed predominantly in liver and kidney. Lower levels in lung and brain. {ECO:0000269|PubMed:8973653, ECO:0000269|PubMed:9141440}.
Pharmacological Animal Models0.012880(Chimpanzee);0.001000(Mouse);0.001516(Rat);0.010526(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1ONI  (X-ray  1.90A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:8973653}. Nucleus {ECO:0000269|PubMed:8973653}. Peroxisome {ECO:0000250|UniProtKB:P52759}. Mitochondrion {ECO:0000250|UniProtKB:P52759}. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear. {ECO:0000269|PubMed:8973653}.
Mouse PG classificationNA
click here to return to the previous page