| Gene Information | |
|---|---|
| Gene Name | TAAR8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 342 |
| Protein Names | Trace amine-associated receptor 8 (TaR-8) (Trace amine receptor 8) (G-protein coupled receptor 102) (Trace amine receptor 5) (TaR-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 12 ( ENSG00000146385 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q969N4 |
| Gene Card | TAAR8 |
| Uniprot ID | Q969N4 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.668351483) |
| Ortholog in Animals | Mouse_ Taar8c ( ortholog_one2many ) Mouse_ Taar8a ( ortholog_one2many ) Mouse_ Taar8b ( ortholog_one2many ) Rat_ Taar8a ( ortholog_one2many ) Rat_ Taar8c ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | HRH2, TAAR6, DRD4, HRH1, DRD1, GPR52, HTR1A, HTR1D, CHRM3, CHRM4, HRH3, TAAR5, HTR4, TAAR1, GPR21, CHRM1, HRH4, TAAR9, CHRM5, DRD3, GPR84, CHRM2, GPR161, DRD5, TAAR2 |
| Tissue | NA |
| Tissue Specificity | Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested. {ECO:0000269|PubMed:11459929}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8192626 rs187426282 rs8192627 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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