| Gene Information | |
|---|---|
| Gene Name | CYP2C19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 490 |
| Protein Names | Cytochrome P450 2C19 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC17) (CYPIIC19) (Cytochrome P450-11A) (Cytochrome P450-254C) (Fenbendazole monooxygenase (4'-hydroxylating)) (EC 1.14.14.75) (Mephenytoin 4-hydroxylase) |
| Target Name | cytochrome p450 2c19 |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000165841 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P33261 |
| Gene Card | CYP2C19 |
| Uniprot ID | P33261 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | yes (1.242106898) |
| Ortholog in Animals | Alpaca_ CYP2C19 ( ortholog_one2one ) |
| Ohnologs | CYP2U1 |
| Paralogs | CYP2C9, CYP2S1, CYP2W1, CYP2D6, CYP2C18, CYP2B6, CYP2C8, CYP2U1, CYP2A6, CYP2A7, CYP2A13, CYP2F1, CYP2R1, CYP2E1, CYP2J2 |
| Tissue | duodenum, liver, small.intestine |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4GQS (X-ray 2.87A ) |
| DBSNP | rs55752064 rs17882687 rs1564657013 rs28399505 rs17878459 rs41291556 rs17885179 rs72552267 rs17884712 rs58973490 rs181297724 rs28399510 rs6413438 rs138142612 rs3758581 rs17879685 rs56337013 rs192154563 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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