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Gene Information
Gene Name
HRINS
Organism
Homo sapiens (Human)
Gene Length
1581
Protein Names
ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
Q09428
Gene Card
ABCC8
Uniprot ID
Q09428
Pfam
PF00664; PF00005
In ASD
yes
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
NA
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
6C3O
(EM
3.90A
)
6C3P
(EM
5.60A
)
7S5V
(EM
3.30A
)
7S5X
(EM
3.70A
)
7S5Y
(EM
3.90A
)
7S5Z
(EM
3.90A
)
7S60
(EM
3.70A
)
7S61
(EM
4.00A
)
DBSNP
rs781059815
rs200670692
rs267606623
rs80356634
rs72559734
rs201682634
rs193929360
rs193929360
rs10400391
rs761749884
rs72559731
rs60637558
rs80356637
rs80356637
rs137852672
rs797045213
rs80356640
rs193929366
rs80356642
rs1048095
rs768017509
rs778892038
rs185040406
rs769569410
rs80356651
rs72559728
rs67254669
rs1420601296
rs372307320
rs1554933168
rs72559727
rs4148619
rs137852674
rs72559726
rs58241708
rs777986828
rs72559723
rs72559723
rs767572066
rs140068774
rs761862121
rs72559721
rs201351976
rs1262517518
rs193922400
rs137852675
rs367850779
rs139964066
rs542157938
rs200563930
rs67767715
rs28936370
rs28936370
rs1953962707
rs757110
rs925231098
rs925231098
rs137852673
rs773448052
rs387906408
rs72559718
rs769279368
rs137852676
rs1446306735
rs28938469
rs80356653
rs387906407
rs1554904565
rs72559717
rs72559716
rs72559715
rs746480424
rs28936371
rs137852671
rs72559713
rs1221760584
rs1320740169
rs8192690
Subcellular location [CC]
Cell membrane {ECO:0000269|PubMed:24814349};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classification
NA
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