Gene Information | |
---|---|
Gene Name | HRIHFB2018 |
Organism | Homo sapiens (Human) |
Gene Length | 646 |
Protein Names | A-kinase anchor protein 8-like (AKAP8-like protein) (Helicase A-binding protein 95) (HAP95) (Homologous to AKAP95 protein) (HA95) (Neighbor of A-kinase-anchoring protein 95) (Neighbor of AKAP95) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | Q9ULX6 |
Gene Card | AKAP8L |
Uniprot ID | Q9ULX6 |
Pfam | PF04988 |
In ASD | no |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Ubiquitously expressed. Expressed in the brain cortex (at protein level). {ECO:0000269|PubMed:10697960, ECO:0000269|PubMed:16391387}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
|
PDB | NA |
DBSNP | rs2058322 |
Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10748171, ECO:0000269|PubMed:10761695}. Nucleus matrix {ECO:0000269|PubMed:11034899, ECO:0000269|PubMed:16391387}. Nucleus speckle {ECO:0000269|PubMed:17594903}. Nucleus, PML body {ECO:0000269|PubMed:11884601}. Cytoplasm {ECO:0000269|PubMed:10748171}. Note=Colocalizes with PRPF40A in the nuclear matrix (PubMed:16391387). Nuclear at steady state but shuttles between the nucleus and cytoplasm (PubMed:10748171). The shuttling property has been questioned (PubMed:11034899). Colocalizes with EBNA-LP in PML bodies (PubMed:11884601). {ECO:0000269|PubMed:10748171, ECO:0000269|PubMed:11034899, ECO:0000269|PubMed:11884601, ECO:0000269|PubMed:16391387}. |
Mouse PG classification | NA |
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