| Gene Information | |
|---|---|
| Gene Name | HRH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) |
| Target Name | histamine h2 receptor |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000113749 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P25021 |
| Gene Card | HRH2 |
| Uniprot ID | P25021 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.038695967) |
| Ortholog in Animals | Alpaca_ HRH2 ( ortholog_one2one ) Dog_ HRH2 ( ortholog_one2one ) GuineaPig_ HRH2 ( ortholog_one2one ) Macaque_ HRH2 ( ortholog_one2one ) Mouse_ Hrh2 ( ortholog_one2one ) Pig_ HRH2 ( ortholog_one2one ) Rat_ Hrh2 ( ortholog_one2one ) Rabbit_ HRH2 ( ortholog_one2one ) |
| Ohnologs | ADRB1, ADRA1A, ADRA1D, ADRB3, DRD5 |
| Paralogs | TAAR6, DRD4, HRH1, DRD1, GPR52, HTR1A, HTR1D, CHRM3, CHRM4, HRH3, TAAR5, HTR4, TAAR1, GPR21, CHRM1, HRH4, TAAR9, CHRM5, TAAR8, DRD3, GPR84, CHRM2, GPR161, DRD5, TAAR2 |
| Tissue | whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7UL3 (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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