| Gene Information | |
|---|---|
| Gene Name | CLEC1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 229 |
| Protein Names | C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000165682 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9P126 |
| Gene Card | CLEC1B |
| Uniprot ID | Q9P126 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | no (-1.124664906) |
| Ortholog in Animals | Alpaca_ CLEC1B ( ortholog_one2one ) GuineaPig_ CLEC1B ( ortholog_one2one ) Macaque_ CLEC1B ( ortholog_one2one ) Mouse_ Clec1b ( ortholog_one2one ) Pig_ CLEC1B ( ortholog_one2one ) Rat_ Clec1b ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD69, CLEC12A, KLRC3, KLRC2, CLEC12B, OLR1, KLRG2, CLEC2A, KLRF1, CLEC1A, KLRF2, KLRD1, CLEC2B, KLRC1, CLEC2L, KLRG1, CLEC9A, KLRC4, KLRK1, CLEC5A, CLEC2D, CLEC7A, KLRB1 |
| Tissue | liver |
| Tissue Specificity | Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. {ECO:0000269|PubMed:10671229, ECO:0000269|PubMed:16174766, ECO:0000269|PubMed:16940507}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C6U (X-ray 1.60A ) 3WSR (X-ray 1.91A ) 3WWK (X-ray 2.98A ) |
| DBSNP | rs612593 rs2273986 rs2273987 rs583903 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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