| Gene Information | |
|---|---|
| Gene Name | HRAS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 189 |
| Protein Names | GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P01111 |
| Gene Card | NRAS |
| Uniprot ID | P01111 |
| Pfam | PF00071 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.071536(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2N9C (NMR - ) 3CON (X-ray 1.65A ) 5UHV (X-ray 1.67A ) 6E6H (X-ray 1.99A ) 6MPP (NMR - ) 6ULI (X-ray 1.88A ) 6ULK (X-ray 1.90A ) 6ULN (X-ray 2.01A ) 6ULR (X-ray 3.20A ) 6UON (X-ray 3.50A ) 6WGH (X-ray 1.65A ) 6ZIO (X-ray 1.55A ) 6ZIR (X-ray 1.90A ) 6ZIZ (X-ray 1.78A ) 7F68 (X-ray 1.24A ) 7OW3 (X-ray 2.46A ) 7OW4 (X-ray 1.81A ) 7OW5 (X-ray 2.58A ) 7OW6 (X-ray 2.64A ) 7PB2 (X-ray 3.41A ) |
| DBSNP | rs121913250 rs121913237 rs121434596 rs121434595 rs397514553 rs267606921 rs267606920 rs121913254 rs11554290 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}; Lipid-anchor {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}; Cytoplasmic side {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}. Golgi apparatus membrane {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}; Lipid-anchor {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}. Note=Shuttles between the plasma membrane and the Golgi apparatus. {ECO:0000269|PubMed:15705808, ECO:0000269|PubMed:26701913}. |
| Mouse PG classification | NA |
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