| Gene Information | |
|---|---|
| Gene Name | CEP135 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1140 |
| Protein Names | Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000174799 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q66GS9 |
| Gene Card | CEP135 |
| Uniprot ID | Q66GS9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.419086148) |
| Ortholog in Animals | Alpaca_ CEP135 ( ortholog_one2one ) Dog_ CEP135 ( ortholog_one2one ) GuineaPig_ CEP135 ( ortholog_one2one ) Macaque_ CEP135 ( ortholog_one2one ) Mouse_ Cep135 ( ortholog_one2one ) Pig_ CEP135 ( ortholog_one2one ) Rat_ Cep135 ( ortholog_one2one ) Rabbit_ CEP135 ( ortholog_one2one ) |
| Ohnologs | TSGA10 |
| Paralogs | CROCC2, TSGA10, CROCC, CEP250 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.008333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5FCN (X-ray 1.80A ) 5NG4 (X-ray 2.14A ) |
| DBSNP | rs3214045 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:32060285}. Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles. |
| Mouse PG classification | NA |
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