| Gene Information | |
|---|---|
| Gene Name | HPS5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1129 |
| Protein Names | BLOC-2 complex member HPS5 (Alpha-integrin-binding protein 63) (Hermansky-Pudlak syndrome 5 protein) (Ruby-eye protein 2 homolog) (Ru2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000110756 ) 3 ( ENSG00000288445 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UPZ3 |
| Gene Card | HPS5 |
| Uniprot ID | Q9UPZ3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.361917541) |
| Ortholog in Animals | Alpaca_ HPS5 ( ortholog_one2one ) Dog_ HPS5 ( ortholog_one2one ) GuineaPig_ HPS5 ( ortholog_one2one ) Macaque_ HPS5 ( ortholog_one2one ) Mouse_ Hps5 ( ortholog_one2one ) Rat_ Hps5 ( ortholog_one2one ) Rabbit_ HPS5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TECPR2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Isoform 1:Highly expressed in lungs and testis. Isoform 2:Highly expressed in placenta, kidney, testis ovary, lung and thymus. {ECO:0000269|PubMed:15296495}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7128017 rs281865102 rs61884288 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:15030569}. |
| Mouse PG classification | HPG |
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