| Gene Information | |
|---|---|
| Gene Name | TSSK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 328 |
| Protein Names | Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) (Serine/threonine-protein kinase 22E) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000139908 ) 3 ( ENSG00000285140 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6SA08 |
| Gene Card | TSSK4 |
| Uniprot ID | Q6SA08 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.814593766) |
| Ortholog in Animals | Alpaca_ TSSK4 ( ortholog_one2one ) Dog_ TSSK4 ( ortholog_one2one ) GuineaPig_ TSSK4 ( ortholog_one2one ) Macaque_ TSSK4 ( ortholog_one2one ) Mouse_ Tssk4 ( ortholog_one2one ) Pig_ TSSK4 ( ortholog_one2one ) Rat_ Tssk4 ( ortholog_one2one ) Rabbit_ TSSK4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TSSK6, SNRK, SIK2, SIK3, NIM1K, NUAK2, TSSK2, SIK1, PRKAA2, BRSK2, NUAK1, BRSK1, HUNK, PRKAA1, TSSK1B, MELK, TSSK3 |
| Tissue | testis |
| Tissue Specificity | Expressed only in the testis. {ECO:0000269|PubMed:15964553}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36036137 rs34083933 rs35468205 rs1270764 rs35244223 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9D411}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9D411}. Note=In spermatozoa, present in the sperm head and in the flagellum. {ECO:0000250|UniProtKB:Q9D411}. |
| Mouse PG classification | NA |
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