| Gene Information | |
|---|---|
| Gene Name | HPGD |
| Organism | Homo sapiens (Human) |
| Gene Length | 266 |
| Protein Names | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Eicosanoid/docosanoid dehydrogenase [NAD(+)]) (EC 1.1.1.-, EC 1.1.1.232) (Prostaglandin dehydrogenase 1) (Short chain dehydrogenase/reductase family 36C member 1) |
| Target Name | 15-hydroxyprostaglandin dehydrogenase [nad(+)] |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000164120 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P15428 |
| Gene Card | HPGD |
| Uniprot ID | P15428 |
| Pfam | PF00106 |
| In ASD | yes |
| Allosteric Prediction | yes (0.668748224) |
| Ortholog in Animals | Alpaca_ HPGD ( ortholog_one2one ) Dog_ HPGD ( ortholog_one2one ) GuineaPig_ Hpgd ( ortholog_one2one ) Macaque_ HPGD ( ortholog_one2one ) Mouse_ Hpgd ( ortholog_one2one ) Pig_ HPGD ( ortholog_one2one ) Rat_ Hpgd ( ortholog_one2one ) Rabbit_ HPGD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in colon epithelium (at protein level). {ECO:0000269|PubMed:15574495}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2GDZ (X-ray 1.65A ) |
| DBSNP | rs121434480 rs121434481 rs140209262 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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