| Gene Information | |
|---|---|
| Gene Name | HP |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain] |
| Target Name | haptoglobin |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000257017 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P00738 |
| Gene Card | HP |
| Uniprot ID | P00738 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | yes (0.820490024) |
| Ortholog in Animals | Dog_ DHODH ( ortholog_one2many ) Mouse_ Hp ( ortholog_one2many ) Rat_ Hp ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | HGFAC, F7, C1R, KLK10, F9, F12, F10, CFI, CFD, PRSS55, PRSS51, C1S, C1RL, KLKB1, F11, HPR |
| Tissue | liver |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WJG (X-ray 3.10A ) 4X0L (X-ray 2.05A ) 5HU6 (X-ray 2.90A ) 6TB2 (X-ray 2.90A ) |
| DBSNP | rs199926732 rs200877317 rs104894517 rs189115161 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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