| Gene Information | |
|---|---|
| Gene Name | P2RX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor) |
| Target Name | p2x purinoceptor 4 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000135124 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q99571 |
| Gene Card | P2RX4 |
| Uniprot ID | Q99571 |
| Pfam | NA |
| In ASD | yes |
| Allosteric Prediction | yes (1.000219797) |
| Ortholog in Animals | Alpaca_ P2RX4 ( ortholog_one2one ) Dog_ P2RX4 ( ortholog_one2one ) GuineaPig_ P2rx4 ( ortholog_one2one ) Macaque_ P2RX4 ( ortholog_one2one ) Mouse_ P2rx4 ( ortholog_one2one ) Pig_ P2RX4 ( ortholog_one2one ) Rat_ P2rx4 ( ortholog_one2one ) Rabbit_ P2RX4 ( ortholog_one2one ) |
| Ohnologs | P2RX6, P2RX1, P2RX3 |
| Paralogs | P2RX7, P2RX3, P2RX1, P2RX2, P2RX6, P2RX5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs200492184 rs1044249 rs765866317 rs25644 rs28360472 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:10515189, ECO:0000269|PubMed:23303206, ECO:0000269|PubMed:28326637}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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