| Gene Information | |
|---|---|
| Gene Name | LIN7B |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104863 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9HAP6 |
| Gene Card | LIN7B |
| Uniprot ID | Q9HAP6 |
| Pfam | PF02828; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.380473893) |
| Ortholog in Animals | Alpaca_ LIN7B ( ortholog_one2one ) Dog_ LIN7B ( ortholog_one2one ) GuineaPig_ LIN7B ( ortholog_one2one ) Macaque_ LIN7B ( ortholog_one2one ) Mouse_ Lin7b ( ortholog_one2one ) Pig_ LIN7B ( ortholog_one2one ) Rat_ Lin7b ( ortholog_one2one ) |
| Ohnologs | LIN7A, LIN7C |
| Paralogs | LIN7C, LIN7A, PDZD11 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DKR (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:O88951}; Peripheral membrane protein {ECO:0000250|UniProtKB:O88951}. Basolateral cell membrane {ECO:0000269|PubMed:11742811, ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000250|UniProtKB:O88951}. Cell junction {ECO:0000250|UniProtKB:O88951}. Postsynaptic density membrane {ECO:0000250|UniProtKB:O88951}; Peripheral membrane protein {ECO:0000250|UniProtKB:O88951}. Cell junction, tight junction {ECO:0000250|UniProtKB:O88951}. Note=Mainly basolateral in renal epithelial cells. {ECO:0000269|PubMed:11742811}. |
| Mouse PG classification | NA |
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