| Gene Information | |
|---|---|
| Gene Name | MAN1A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000198162 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60476 |
| Gene Card | MAN1A2 |
| Uniprot ID | O60476 |
| Pfam | PF01532 |
| In ASD | no |
| Allosteric Prediction | no (-1.137304201) |
| Ortholog in Animals | Alpaca_ MAN1A2 ( ortholog_one2one ) Dog_ MAN1A2 ( ortholog_one2one ) GuineaPig_ MAN1A2 ( ortholog_one2one ) Macaque_ MAN1A2 ( ortholog_one2one ) Mouse_ Man1a2 ( ortholog_one2one ) Pig_ MAN1A2 ( ortholog_one2one ) Rat_ Man1a2 ( ortholog_one2one ) Rabbit_ MAN1A2 ( ortholog_one2one ) |
| Ohnologs | MAN1A1, MAN1C1 |
| Paralogs | MAN1A1, MAN1B1, EDEM1, EDEM2, EDEM3, MAN1C1 |
| Tissue | substantia.nigra |
| Tissue Specificity | Highest levels of expression in placenta and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Mouse PG classification | NA |
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