| Gene Information | |
|---|---|
| Gene Name | ITPRIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 547 |
| Protein Names | Inositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000148841 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IWB1 |
| Gene Card | ITPRIP |
| Uniprot ID | Q8IWB1 |
| Pfam | PF20266 |
| In ASD | no |
| Allosteric Prediction | no (-1.555581459) |
| Ortholog in Animals | Alpaca_ ITPRIP ( ortholog_one2one ) GuineaPig_ ITPRIP ( ortholog_one2one ) Macaque_ ITPRIP ( ortholog_one2one ) Mouse_ Itprip ( ortholog_one2one ) Pig_ ITPRIP ( ortholog_one2one ) Rat_ Itprip ( ortholog_one2one ) Rabbit_ ITPRIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ITPRIPL1, ITPRIPL2, MAB21L3, MAB21L4, MAB21L1, CGAS, MAB21L2, MB21D2, TMEM102 |
| Tissue | bone.marrow, breast, heart, left.atrium, left.ventricle, lung, mitral.valve, ovary, tricuspid.valve, zone.of.skin |
| Tissue Specificity | Detected in brain where it is concentrated in cerebellar Purkinje cells (at protein level). {ECO:0000269|PubMed:16990268}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16990268}; Single-pass type I membrane protein. Nucleus outer membrane {ECO:0000250|UniProtKB:Q3TNL8}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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