| Gene Information | |
|---|---|
| Gene Name | HOPX |
| Organism | Homo sapiens (Human) |
| Gene Length | 73 |
| Protein Names | Homeodomain-only protein (Lung cancer-associated Y protein) (Not expressed in choriocarcinoma protein 1) (Odd homeobox protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000171476 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BPY8 |
| Gene Card | HOPX |
| Uniprot ID | Q9BPY8 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-1.072162987) |
| Ortholog in Animals | Alpaca_ HOPX ( ortholog_one2one ) Dog_ SPINK2 ( ortholog_one2one ) GuineaPig_ HOPX ( ortholog_one2one ) Macaque_ HOPX ( ortholog_one2one ) Mouse_ Hopx ( ortholog_one2one ) Rat_ Hopx ( ortholog_one2one ) Rabbit_ HOPX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | lung |
| Tissue Specificity | Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. {ECO:0000269|PubMed:12573257, ECO:0000269|PubMed:12759545}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q8R1H0}. Cytoplasm {ECO:0000250|UniProtKB:Q8R1H0}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |