| Gene Information | |
|---|---|
| Gene Name | FAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 4557 |
| Protein Names | Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000165323 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | FAT3 |
| Uniprot ID | Q8TDW7 |
| Pfam | PF00028; PF02210 |
| In ASD | no |
| Allosteric Prediction | no (-1.155855298) |
| Ortholog in Animals | Alpaca_ FAT3 ( ortholog_one2one ) Macaque_ FAT3 ( ortholog_one2one ) Mouse_ Fat3 ( ortholog_one2one ) Rat_ Fat3 ( ortholog_one2one ) Rabbit_ FAT3 ( ortholog_one2one ) |
| Ohnologs | FAT1, FAT2 |
| Paralogs | CELSR3, FAT2, FAT1, CELSR1, FAT4, CELSR2 |
| Tissue | NA |
| Tissue Specificity | Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. {ECO:0000269|PubMed:16865240}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10830902 rs16917409 rs11821058 rs7949157 rs16918105 rs17615477 rs3847531 rs10765565 rs4753069 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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