| Gene Information | |
|---|---|
| Gene Name | GRB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43639 |
| Gene Card | NCK2 |
| Uniprot ID | O43639 |
| Pfam | PF00017; PF00018; PF14604 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001466(Rat);0.021212(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1U5S (NMR - ) 1WX6 (NMR - ) 1Z3K (NMR - ) 2B86 (NMR - ) 2CIA (X-ray 1.45A ) 2FRW (NMR - ) 2FRY (NMR - ) 2JXB (NMR - ) 4E6R (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16835242}. Endoplasmic reticulum {ECO:0000269|PubMed:16835242}. |
| Mouse PG classification | NA |
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