| Gene Information | |
|---|---|
| Gene Name | HNRNPL |
| Organism | Homo sapiens (Human) |
| Gene Length | 589 |
| Protein Names | Heterogeneous nuclear ribonucleoprotein L (hnRNP L) |
| Target Name | heterogeneous nuclear ribonucleoprotein l |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000104824 ) 3 ( ENSG00000282947 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P14866 |
| Gene Card | HNRNPL |
| Uniprot ID | P14866 |
| Pfam | PF00076; PF11835 |
| In ASD | no |
| Allosteric Prediction | yes (1.019934892) |
| Ortholog in Animals | Alpaca_ HNRNPL ( ortholog_one2one ) Dog_ HNRNPL ( ortholog_one2one ) GuineaPig_ HNRNPL ( ortholog_one2one ) Macaque_ HNRNPL ( ortholog_one2one ) Mouse_ Hnrnpl ( ortholog_one2one ) Pig_ HNRNPL ( ortholog_one2one ) Rat_ Hnrnpl ( ortholog_one2one ) Rabbit_ HNRNPL ( ortholog_one2one ) |
| Ohnologs | HNRNPLL |
| Paralogs | RBM20, HNRNPLL, PTBP3, PTBP2, PTBP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001240(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3R27 (X-ray 2.04A ) 3TO8 (X-ray 1.82A ) 7EVR (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:17289661, ECO:0000269|PubMed:2687284, ECO:0000305|PubMed:26051023}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules. {ECO:0000269|PubMed:17289661}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |