| Gene Information | |
|---|---|
| Gene Name | HNRNPK |
| Organism | Homo sapiens (Human) |
| Gene Length | 463 |
| Protein Names | Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP) |
| Target Name | heterogeneous nuclear ribonucleoprotein k |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000165119 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P61978 |
| Gene Card | HNRNPK |
| Uniprot ID | P61978 |
| Pfam | PF00013; PF08067 |
| In ASD | no |
| Allosteric Prediction | yes (0.545681552) |
| Ortholog in Animals | Alpaca_ HNRNPK ( ortholog_one2one ) Dog_ HNRNPK ( ortholog_one2many ) Macaque_ HNRNPK ( ortholog_one2one ) Mouse_ Hnrnpk ( ortholog_one2one ) Rat_ Hnrnpk ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NOVA2, FUBP3, FUBP1, IGF2BP1, KHSRP, PCBP4, PCBP3, PCBP1, IGF2BP3, IGF2BP2, NOVA1, PCBP2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1J5K (NMR - ) 1KHM (NMR - ) 1ZZI (X-ray 1.80A ) 1ZZJ (X-ray 2.30A ) 1ZZK (X-ray 0.95A ) 7CRU (X-ray 2.80A ) 7RJK (X-ray 1.85A ) 7RJO (X-ray 1.38A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:1729596}. Nucleus, nucleoplasm {ECO:0000269|PubMed:16360036, ECO:0000269|PubMed:1729596, ECO:0000269|PubMed:18775702, ECO:0000269|PubMed:22721921}. Cell projection, podosome {ECO:0000269|PubMed:22721921}. Note=Recruited to p53/TP53-responsive promoters, in the presence of functional p53/TP53 (PubMed:16360036). In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear (PubMed:18775702). |
| Mouse PG classification | NA |
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