| Gene Information | |
|---|---|
| Gene Name | HNMT |
| Organism | Homo sapiens (Human) |
| Gene Length | 292 |
| Protein Names | Histamine N-methyltransferase (HMT) (EC 2.1.1.8) |
| Target Name | histamine n-methyltransferase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000150540 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50135 |
| Gene Card | HNMT |
| Uniprot ID | P50135 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.843235135) |
| Ortholog in Animals | Alpaca_ HNMT ( ortholog_one2one ) Dog_ HNMT ( ortholog_one2one ) GuineaPig_ HNMT ( ortholog_one2one ) Macaque_ HNMT ( ortholog_one2one ) Mouse_ Hnmt ( ortholog_one2one ) Pig_ HNMT ( ortholog_one2one ) Rat_ Hnmt ( ortholog_one2one ) Rabbit_ HNMT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JQD (X-ray 2.28A ) 1JQE (X-ray 1.91A ) 2AOT (X-ray 1.90A ) 2AOU (X-ray 2.30A ) 2AOV (X-ray 2.48A ) 2AOW (X-ray 2.97A ) 2AOX (X-ray 3.12A ) |
| DBSNP | rs758252808 rs11558538 rs745756308 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:26206890}. |
| Mouse PG classification | NA |
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