| Gene Information | |
|---|---|
| Gene Name | DUOXA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | Dual oxidase maturation factor 2 (Dual oxidase activator 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000140274 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q1HG44 |
| Gene Card | DUOXA2 |
| Uniprot ID | Q1HG44 |
| Pfam | PF10204 |
| In ASD | no |
| Allosteric Prediction | no (-0.714145994) |
| Ortholog in Animals | Alpaca_ DUOXA2 ( ortholog_one2one ) GuineaPig_ DUOXA2 ( ortholog_one2one ) Macaque_ DUOXA2 ( ortholog_one2one ) Mouse_ Duoxa2 ( ortholog_one2one ) Pig_ DUOXA2 ( ortholog_one2one ) Rat_ Duoxa2 ( ortholog_one2one ) Rabbit_ DUOXA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DUOXA1 |
| Tissue | gall.bladder, vas.deferens |
| Tissue Specificity | Specifically expressed in thyroid. Also detected in salivary glands. {ECO:0000269|PubMed:16651268}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2576090 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16651268}; Multi-pass membrane protein {ECO:0000269|PubMed:16651268}. |
| Mouse PG classification | LPG |
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