| Gene Information | |
|---|---|
| Gene Name | LRRC17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 441 |
| Protein Names | Leucine-rich repeat-containing protein 17 (p37NB) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000128606 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N6Y2 |
| Gene Card | LRRC17 |
| Uniprot ID | Q8N6Y2 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.557237747) |
| Ortholog in Animals | Alpaca_ LRRC17 ( ortholog_one2one ) Dog_ LRRC17 ( ortholog_one2one ) GuineaPig_ LRRC17 ( ortholog_one2one ) Macaque_ LRRC17 ( ortholog_one2one ) Mouse_ Lrrc17 ( ortholog_one2one ) Pig_ LRRC17 ( ortholog_one2one ) Rat_ Lrrc17 ( ortholog_one2one ) Rabbit_ LRRC17 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD180, RXFP1, TLR8, NRROS, TLR5, TSKU, TLR7, TLR10, RXFP2, TLR6, LRRC3B, IGFALS, TLR3, TLR2, TLR4, LRRC32, LRRC53, VASN, TLR1, LRRC3C, LRRC3, LRIT2 |
| Tissue | ovary |
| Tissue Specificity | Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells. {ECO:0000269|PubMed:19336404, ECO:0000269|PubMed:8982252}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34613342 rs3800939 rs1057066 |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000250}. |
| Mouse PG classification | NA |
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