| Gene Information | |
|---|---|
| Gene Name | EHD4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000103966 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H223 |
| Gene Card | EHD4 |
| Uniprot ID | Q9H223 |
| Pfam | PF18150; PF00350; PF12763; PF16880 |
| In ASD | no |
| Allosteric Prediction | no (-0.149456205) |
| Ortholog in Animals | Alpaca_ EHD4 ( ortholog_one2one ) Dog_ EHD4 ( ortholog_one2one ) GuineaPig_ EHD4 ( ortholog_one2one ) Macaque_ EHD4 ( ortholog_one2one ) Mouse_ Ehd4 ( ortholog_one2one ) Pig_ EHD4 ( ortholog_one2one ) Rat_ Ehd4 ( ortholog_one2one ) Rabbit_ EHD4 ( ortholog_one2one ) |
| Ohnologs | EHD2, EHD3, EHD1 |
| Paralogs | EPS15L1, REPS2, ITSN2, SRL, EPS15, ITSN1, EHD2, EHD3, REPS1, EHD1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in pancreas and heart. {ECO:0000269|PubMed:10673336}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11549015 |
| Subcellular location [CC] | Early endosome membrane {ECO:0000269|PubMed:18331452}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Recycling endosome membrane {ECO:0000269|PubMed:18331452}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell membrane {ECO:0000250|UniProtKB:Q9EQP2}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |