Gene Information
Gene NameHLA-DRB4
OrganismHomo sapiens (Human)
Gene Length266
Protein NamesHLA class II histocompatibility antigen, DR beta 4 chain (MHC class II antigen DRB4)
Target Namehla-dr
Target TypeNA
Gene Age3 ( ENSG00000227357 )
3 ( ENSG00000227826 )
3 ( ENSG00000231021 )
Evolutionary StageVertebrata
AlphaFoldDBP13762
Gene CardHLA-DRB4
Uniprot IDP13762
PfamPF07654; PF00969
In ASDno
Allosteric Predictionyes (0.275663958)
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane;
Single-pass type I membrane protein. Endoplasmic reticulum membrane;
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane;
Single-pass type I membrane protein. Endosome membrane;
Single-pass type I membrane protein. Lysosome membrane;
Single-pass type I membrane protein. Late endosome membrane;
Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Mouse PG classificationNA
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