| Gene Information | |
|---|---|
| Gene Name | HLA-DQB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000179344 ) 3 ( ENSG00000206237 ) 3 ( ENSG00000206302 ) 3 ( ENSG00000225824 ) 3 ( ENSG00000231286 ) 3 ( ENSG00000231939 ) 3 ( ENSG00000233209 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01920 |
| Gene Card | HLA-DQB1 |
| Uniprot ID | P01920 |
| Pfam | PF07654; PF00969 |
| In ASD | no |
| Allosteric Prediction | yes (0.36775177) |
| Ortholog in Animals | Alpaca_ HLA-DQB1 ( ortholog_one2one ) Mouse_ H2-Ab1 ( ortholog_one2many ) Pig_ SLA-DQB1 ( ortholog_many2many ) Rat_ RT1-Bb ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | HLA-DPB1, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DQA1, HLA-DQA2, HLA-DOB, HLA-DRA, HLA-DRB5, HLA-DRB1, B2M, HLA-DMA, HLA-DQB2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JK8 (X-ray 2.40A ) 1S9V (X-ray 2.22A ) 1UVQ (X-ray 1.80A ) 2NNA (X-ray 2.10A ) 4GG6 (X-ray 3.20A ) 4OZF (X-ray 2.70A ) 4OZG (X-ray 3.00A ) 4OZH (X-ray 2.80A ) 4OZI (X-ray 3.20A ) |
| DBSNP | rs1049056 rs1049057 rs3189152 rs3891176 rs1049059 rs1049060 rs1049060 rs1049062 rs1049061 rs1130366 rs12722106 rs9274407 rs56173496 rs1130375 rs1130368 rs41540813 rs766817072 rs41563539 rs9274405 rs281862065 rs281874782 rs45519640 rs1063318 rs1049083 rs9274398 rs9274397 rs41558214 rs9274395 rs1140313 rs1130380 rs1130380 rs1130380 rs1130381 rs1071637 rs1071637 rs41562414 rs1130382 rs41556215 rs9274390 rs41563814 rs9274390 rs1130386 rs1130390 rs1130387 rs9274384 rs1130392 rs1140316 rs1140317 rs9274380 rs9274380 rs9274379 rs1140320 rs1049100 rs1063322 rs41542812 rs41544112 rs9273989 rs63626961 rs2647032 rs9273981 rs1063323 rs9273952 rs9273948 rs701564 rs80255621 rs1130398 rs1130399 rs281864132 rs1130429 rs1049163 rs1140342 rs1140343 rs1130432 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. |
| Mouse PG classification | NA |
| click here to return to the previous page | |