| Gene Information | |
|---|---|
| Gene Name | HLA-DPB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 258 |
| Protein Names | HLA class II histocompatibility antigen, DP beta 1 chain (HLA class II histocompatibility antigen, DP(W4) beta chain) (MHC class II antigen DPB1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000215048 ) 382 ( ENSG00000223865 ) 3 ( ENSG00000226826 ) 3 ( ENSG00000229295 ) 3 ( ENSG00000230708 ) 3 ( ENSG00000230763 ) 3 ( ENSG00000236693 ) 3 ( ENSG00000237710 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P04440 |
| Gene Card | HLA-DPB1 |
| Uniprot ID | P04440 |
| Pfam | PF07654; PF00969 |
| In ASD | no |
| Allosteric Prediction | no (-0.085561013) |
| Ortholog in Animals | Alpaca_ HLA-DPB1 ( ortholog_one2one ) Rat_ AC098547.2 ( ortholog_one2one ) Rabbit_ HLA-DPB1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DQA1, HLA-DQA2, HLA-DOB, HLA-DRA, HLA-DRB5, HLA-DRB1, B2M, HLA-DQB1, HLA-DQB2, HLA-DMA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LQZ (X-ray 3.25A ) 4P4K (X-ray 2.80A ) 4P4R (X-ray 3.00A ) 4P57 (X-ray 2.60A ) 4P5K (X-ray 2.59A ) 4P5M (X-ray 1.70A ) |
| DBSNP | rs41558014 rs11551416 rs1126504 rs12722013 rs1126509 rs386699869 rs1126513 rs41540313 rs1424116907 rs41555313 rs41555313 rs41553416 rs41561114 rs12722018 rs9277348 rs1042117 rs1042121 rs77062860 rs41552915 rs707958 rs386699870 rs707958 rs1042131 rs1042133 rs41545212 rs41550319 rs41560812 rs1042136 rs1042136 rs41547212 rs1042140 rs12722027 rs41554314 rs41546618 rs41551920 rs1042153 rs1042151 rs1042169 rs1042169 rs9277354 rs9277355 rs9277356 rs41541915 rs1126537 rs1042335 rs14362 rs9276 rs11551421 rs3097675 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. |
| Mouse PG classification | NA |
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