Gene Information
Gene NameHLA-DP1B
OrganismHomo sapiens (Human)
Gene Length258
Protein NamesHLA class II histocompatibility antigen, DP beta 1 chain (HLA class II histocompatibility antigen, DP(W4) beta chain) (MHC class II antigen DPB1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP04440
Gene CardHLA-DPB1
Uniprot IDP04440
PfamPF07654; PF00969
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3LQZ  (X-ray  3.25A  4P4K  (X-ray  2.80A  4P4R  (X-ray  3.00A  4P57  (X-ray  2.60A  4P5K  (X-ray  2.59A  4P5M  (X-ray  1.70A 
DBSNP rs41558014  rs11551416  rs1126504  rs12722013  rs1126509  rs386699869  rs1126513  rs41540313  rs1424116907  rs41555313  rs41555313  rs41553416  rs41561114  rs12722018  rs9277348  rs1042117  rs1042121  rs77062860  rs41552915  rs707958  rs386699870  rs707958  rs1042131  rs1042133  rs41545212  rs41550319  rs41560812  rs1042136  rs1042136  rs41547212  rs1042140  rs12722027  rs41554314  rs41546618  rs41551920  rs1042153  rs1042151  rs1042169  rs1042169  rs9277354  rs9277355  rs9277356  rs41541915  rs1126537  rs1042335  rs14362  rs9276  rs11551421  rs3097675 
Subcellular location [CC]Cell membrane;
Single-pass type I membrane protein. Endoplasmic reticulum membrane;
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane;
Single-pass type I membrane protein. Endosome membrane;
Single-pass type I membrane protein. Lysosome membrane;
Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Mouse PG classificationNA
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