| Gene Information | |
|---|---|
| Gene Name | HDAC10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 669 |
| Protein Names | Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10) |
| Target Name | histone deacetylase 10 |
| Target Type | Patented-recorded target |
| Gene Age | 645 ( ENSG00000100429 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q969S8 |
| Gene Card | HDAC10 |
| Uniprot ID | Q969S8 |
| Pfam | PF00850 |
| In ASD | no |
| Allosteric Prediction | yes (0.389164458) |
| Ortholog in Animals | Alpaca_ HDAC10 ( ortholog_one2one ) Dog_ HDAC10 ( ortholog_one2one ) Macaque_ HDAC10 ( ortholog_one2one ) Mouse_ Hdac10 ( ortholog_one2one ) Pig_ HDAC10 ( ortholog_one2one ) Rat_ Hdac10 ( ortholog_one2one ) Rabbit_ HDAC10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HDAC4, HDAC11, HDAC8, HDAC3, HDAC7, HDAC6, HDAC2, HDAC1, HDAC5, HDAC9 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high levels in liver and kidney. {ECO:0000269|PubMed:11677242, ECO:0000269|PubMed:11739383, ECO:0000269|PubMed:11861901}. |
| Pharmacological Animal Models | 0.032198(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34402301 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11677242, ECO:0000269|PubMed:11726666, ECO:0000269|PubMed:11739383, ECO:0000269|PubMed:11861901, ECO:0000269|PubMed:23801752}. Nucleus {ECO:0000269|PubMed:11677242, ECO:0000269|PubMed:11726666, ECO:0000269|PubMed:11739383, ECO:0000269|PubMed:11861901}. Note=Excluded from nucleoli. {ECO:0000269|PubMed:11726666}. |
| Mouse PG classification | NA |
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