Gene Information
Gene NameLRRCC1
OrganismHomo sapiens (Human)
Gene Length1032
Protein NamesLeucine-rich repeat and coiled-coil domain-containing protein 1 (Centrosomal leucine-rich repeat and coiled-coil domain-containing protein)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000133739 )
Evolutionary StageEukaryota
AlphaFoldDBQ9C099
Gene CardLRRCC1
Uniprot IDQ9C099
PfamNA
In ASDno
Allosteric Predictionno (-1.644889258)
Ortholog in AnimalsAlpaca_ LRRCC1 ( ortholog_one2one )
Dog_ LRRCC1 ( ortholog_one2one )
Macaque_ LRRCC1 ( ortholog_one2one )
Mouse_ Lrrcc1 ( ortholog_one2one )
Pig_ LRRCC1 ( ortholog_one2one )
Rat_ Lrrcc1 ( ortholog_one2one )
Rabbit_ LRRCC1 ( ortholog_one2one )
OhnologsNA
ParalogsLRRC43, DNAAF11, DRC3, LRRC9, LRRC46, DNAAF1, LRRC49, CEP97, LRRC23, PPP1R42, LRRC61, LRRIQ3, LRGUK
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs16913589  rs3736038  rs6985225 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:18728398}. Note=Associates with the centrosome throughout the cell cycle and extensively accumulates during the mitotic phase.
Mouse PG classificationNA
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