| Gene Information | |
|---|---|
| Gene Name | HIPI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 336 |
| Protein Names | E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99496 |
| Gene Card | RNF2 |
| Uniprot ID | Q99496 |
| Pfam | PF16207 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.037681(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H0D (X-ray 2.50A ) 3GS2 (X-ray 1.70A ) 3H8H (X-ray 2.00A ) 3IXS (X-ray 1.70A ) 3RPG (X-ray 2.65A ) 4R8P (X-ray 3.28A ) 4S3O (X-ray 2.00A ) 6WI7 (X-ray 1.70A ) 6WI8 (X-ray 3.09A ) 7ND1 (NMR - ) |
| DBSNP | rs1651767648 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21282530}. Cytoplasm {ECO:0000250|UniProtKB:Q9CQJ4}. Chromosome {ECO:0000250|UniProtKB:Q9CQJ4}. Note=Enriched on inactive X chromosome (Xi) in female trophoblast stem (TS) cells as well as differentiating embryonic stem (ES) cells. The enrichment on Xi is transient during TS and ES cell differentiation. The association with Xi is mitotically stable in non-differentiated TS cells. {ECO:0000250|UniProtKB:Q9CQJ4}. |
| Mouse PG classification | NA |
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