| Gene Information | |
|---|---|
| Gene Name | NECTIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 517 |
| Protein Names | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000110400 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15223 |
| Gene Card | NECTIN1 |
| Uniprot ID | Q15223 |
| Pfam | PF08205; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.172683641) |
| Ortholog in Animals | Alpaca_ NECTIN1 ( ortholog_one2one ) Dog_ NECTIN1 ( ortholog_one2one ) GuineaPig_ NECTIN1 ( ortholog_one2one ) Macaque_ NECTIN1 ( ortholog_one2one ) Mouse_ Nectin1 ( ortholog_one2one ) Pig_ NECTIN1 ( ortholog_one2one ) Rat_ Nectin1 ( ortholog_one2one ) Rabbit_ NECTIN1 ( ortholog_one2one ) |
| Ohnologs | PVR, NECTIN2, NECTIN4, NECTIN3 |
| Paralogs | TIGIT, NCR3, CD200, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, CADM4, SMAGP, CADM1, CD226, PVR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ALP (X-ray 2.80A ) 3SKU (X-ray 4.00A ) 3U82 (X-ray 3.16A ) 3U83 (X-ray 2.50A ) 4FMF (X-ray 3.20A ) 4MYW (X-ray 3.19A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein. Presynaptic cell membrane {ECO:0000250}.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Gamma]: Secreted. |
| Mouse PG classification | NA |
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