| Gene Information | |
|---|---|
| Gene Name | LAPTM4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 317 |
| Protein Names | Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104341 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86VI4 |
| Gene Card | LAPTM4B |
| Uniprot ID | Q86VI4 |
| Pfam | PF03821 |
| In ASD | no |
| Allosteric Prediction | no (-0.668372177) |
| Ortholog in Animals | Alpaca_ LAPTM4B ( ortholog_one2many ) Dog_ LAPTM4B ( ortholog_one2one ) GuineaPig_ LAPTM4B ( ortholog_one2one ) Macaque_ LAPTM4B ( ortholog_one2one ) Mouse_ Laptm4b ( ortholog_one2one ) Pig_ LAPTM4B ( ortholog_one2one ) Rat_ Laptm4b ( ortholog_one2one ) Rabbit_ LAPTM4B ( ortholog_one2one ) |
| Ohnologs | LAPTM4A |
| Paralogs | LAPTM4A, LAPTM5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:12902989}; Multi-pass membrane protein {ECO:0000269|PubMed:12902989}. Late endosome membrane {ECO:0000269|PubMed:21224396, ECO:0000269|PubMed:22096579, ECO:0000269|PubMed:25588945}. Cell membrane {ECO:0000269|PubMed:22096579}. Cell projection {ECO:0000269|PubMed:22096579}. Lysosome membrane {ECO:0000269|PubMed:21224396, ECO:0000269|PubMed:22096579}. Endosome membrane. Endosome, multivesicular body membrane {ECO:0000269|PubMed:26280656}. Endosome, multivesicular body lumen {ECO:0000269|PubMed:26280656}. |
| Mouse PG classification | NA |
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