| Gene Information | |
|---|---|
| Gene Name | NT5DC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | 5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000111696 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86UY8 |
| Gene Card | NT5DC3 |
| Uniprot ID | Q86UY8 |
| Pfam | PF05761 |
| In ASD | no |
| Allosteric Prediction | no (-0.310941363) |
| Ortholog in Animals | Alpaca_ NT5DC3 ( ortholog_one2one ) Dog_ NT5DC3 ( ortholog_one2one ) GuineaPig_ NT5DC3 ( ortholog_one2one ) Mouse_ Nt5dc3 ( ortholog_one2one ) Pig_ NT5DC3 ( ortholog_one2one ) Rat_ Nt5dc3 ( ortholog_one2one ) Rabbit_ NT5DC3 ( ortholog_one2one ) |
| Ohnologs | NT5DC2 |
| Paralogs | NT5DC4, NT5C2, NT5DC1, NT5DC2 |
| Tissue | sigmoid.colon |
| Tissue Specificity | Expressed in brain, placenta, skeletal muscle, pancreas, testis, uterus, and small intestine. Reduced expression in pancreatic cancer cells. {ECO:0000269|PubMed:15547748}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12184494 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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