Gene Information
Gene NameRBM14
OrganismHomo sapiens (Human)
Gene Length669
Protein NamesRNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000239306 )
Evolutionary StageEukaryota
AlphaFoldDBQ96PK6
Gene CardRBM14
Uniprot IDQ96PK6
PfamPF00076
In ASDno
Allosteric Predictionno (-0.420207175)
Ortholog in AnimalsAlpaca_ RBM4 ( ortholog_one2one )
Dog_ RBM14 ( ortholog_one2one )
GuineaPig_ RBM14 ( ortholog_one2one )
Macaque_ RBM14 ( ortholog_one2one )
Mouse_ Rbm14 ( ortholog_one2one )
Pig_ RBM14 ( ortholog_one2one )
Rat_ Rbm14 ( ortholog_one2one )
OhnologsNA
ParalogsRBMS2, PABPC1, PABPC3, RBM24, ELAVL4, ELAVL3, RBMS1, ELAVL2, PUF60, RBM34, RBM45, HNRNPR, SYNCRIP, PABPC1L, PABPC5, PABPC1L2A, PABPC1L2B, SF3B4, RBM38, ELAVL1, TARDBP, RBMS3, PABPC4, PABPC4L
TissueNA
Tissue SpecificityExpressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2DNP  (NMR  -  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:25385835}. Nucleus, nucleolus {ECO:0000269|PubMed:11790299}. Cytoplasm {ECO:0000269|PubMed:25385835}. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles (PubMed:11790299). Cytoplasmic localization is crucial for its function in suppressing the formation of aberrant centriolar protein complexes (PubMed:25385835). {ECO:0000269|PubMed:11790299, ECO:0000269|PubMed:25385835}.
Mouse PG classificationNA
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