Gene Information
Gene NameHID1
OrganismHomo sapiens (Human)
Gene Length788
Protein NamesProtein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000167861 )
Evolutionary StageEukaryota
AlphaFoldDBQ8IV36
Gene CardHID1
Uniprot IDQ8IV36
PfamPF12722
In ASDno
Allosteric Predictionno (-1.036766764)
Ortholog in AnimalsAlpaca_ HID1 ( ortholog_one2one )
Dog_ HID1 ( ortholog_one2one )
GuineaPig_ HID1 ( ortholog_one2one )
Macaque_ HID1 ( ortholog_one2one )
Mouse_ Hid1 ( ortholog_one2one )
Pig_ HID1 ( ortholog_one2one )
Rat_ Hid1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines. {ECO:0000269|PubMed:11281419, ECO:0000269|PubMed:21337012}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:21337012}. Golgi apparatus membrane {ECO:0000269|PubMed:21337012};
Lipid-anchor {ECO:0000269|PubMed:21337012}. Note=Shuttles between the cytosol and the Golgi apparatus.
Mouse PG classificationNA
click here to return to the previous page