| Gene Information | |
|---|---|
| Gene Name | COL16A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1604 |
| Protein Names | Collagen alpha-1(XVI) chain |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000084636 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q07092 |
| Gene Card | COL16A1 |
| Uniprot ID | Q07092 |
| Pfam | PF01391 |
| In ASD | no |
| Allosteric Prediction | no (-0.441791561) |
| Ortholog in Animals | Alpaca_ COL16A1 ( ortholog_one2one ) Dog_ COL16A1 ( ortholog_one2one ) GuineaPig_ COL16A1 ( ortholog_one2one ) Macaque_ COL16A1 ( ortholog_one2one ) Mouse_ Col16a1 ( ortholog_one2one ) Pig_ COL16A1 ( ortholog_one2one ) Rat_ Col16a1 ( ortholog_one2one ) Rabbit_ COL16A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | COL9A2, COLQ, COL4A1, COL17A1, COL1A1, EDA, COL22A1, COL11A1, COL15A1, COL9A3, COL26A1, COL13A1, COL7A1, COL5A1, COL25A1, COL3A1, COL6A2, COL5A3, COL27A1, COL1A2, COL24A1, COL5A2, COL18A1, COL9A1, COL23A1, COL2A1, COL4A2, COL20A1, COL4A4, COL4A6, COL28A1, COL11A2, COL21A1, COL6A1, EMID1, COL4A5, COL4A3 |
| Tissue | NA |
| Tissue Specificity | In papillary dermis, is a component of specialized fibrillin-1-containing microfibrils, whereas in territorial cartilage matrix, it is localized to a discrete population of thin, weakly banded collagen fibrils in association with other collagens (at protein level). In the placenta, where it is found in the amnion, a membranous tissue lining the amniotic cavity. Within the amnion, it is found in an acellular, relatively dense layer of a complex network of reticular fibers. Also located to a fibroblast layer beneath this dense layer. Exists in tissues in association with other types of collagen. {ECO:0000269|PubMed:12782140}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2228552 rs6699645 rs34770879 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:9022684}. |
| Mouse PG classification | NA |
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