Gene Information | |
---|---|
Gene Name | HGF |
Organism | Homo sapiens (Human) |
Gene Length | 728 |
Protein Names | Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain] |
Target Name | hepatocyte growth factor |
Target Type | Clinical trial target |
Gene Age | 645 ( ENSG00000019991 ) |
Evolutionary Stage | Eukaryota |
AlphaFoldDB | P14210 |
Gene Card | HGF |
Uniprot ID | P14210 |
Pfam | PF00051; PF00024; PF00089 |
In ASD | yes |
Allosteric Prediction | yes (1.514908313) |
Ortholog in Animals | Alpaca_ HGF ( ortholog_one2one ) Dog_ HGF ( ortholog_one2one ) GuineaPig_ HGF ( ortholog_one2one ) Macaque_ HGF ( ortholog_one2one ) Mouse_ Hgf ( ortholog_one2one ) Pig_ HGF ( ortholog_one2one ) Rat_ Hgf ( ortholog_one2one ) Rabbit_ HGF ( ortholog_one2one ) |
Ohnologs | PLG, MST1, LPA |
Paralogs | GZMA, MST1, PIK3IP1, HABP2, GZMK |
Tissue | placenta |
Tissue Specificity | NA |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 1BHT (X-ray 2.00A ) 1GMN (X-ray 2.30A ) 1GMO (X-ray 3.00A ) 1GP9 (X-ray 2.50A ) 1NK1 (X-ray 2.50A ) 1SHY (X-ray 3.22A ) 1SI5 (X-ray 2.53A ) 2HGF (NMR - ) 2QJ2 (X-ray 1.81A ) 3HMS (X-ray 1.70A ) 3HMT (X-ray 2.00A ) 3HN4 (X-ray 2.60A ) 3MKP (X-ray 2.81A ) 3SP8 (X-ray 1.86A ) 4D3C (X-ray 2.62A ) 4K3J (X-ray 2.80A ) 4O3T (X-ray 2.99A ) 4O3U (X-ray 3.04A ) 5COE (X-ray 2.18A ) 5CP9 (X-ray 1.90A ) 5CS1 (X-ray 2.00A ) 5CS3 (X-ray 2.50A ) 5CS5 (X-ray 1.90A ) 5CS9 (X-ray 2.00A ) 5CSQ (X-ray 1.95A ) 5CT1 (X-ray 2.00A ) 5CT2 (X-ray 2.00A ) 5CT3 (X-ray 2.00A ) 7MO7 (EM 4.80A ) 7MO8 (EM 4.50A ) 7MO9 (EM 4.00A ) 7MOA (EM 4.90A ) 7MOB (EM 5.00A ) 7OCL (X-ray 1.80A ) 7OCM (X-ray 1.70A ) |
DBSNP | rs5745687 rs5745688 |
Subcellular location [CC] | NA |
Mouse PG classification | NA |
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