| Gene Information | |
|---|---|
| Gene Name | HFM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1435 |
| Protein Names | Probable ATP-dependent DNA helicase HFM1 (EC 3.6.4.12) (SEC63 domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000162669 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | A2PYH4 |
| Gene Card | HFM1 |
| Uniprot ID | A2PYH4 |
| Pfam | PF00270; PF00271; PF02889 |
| In ASD | no |
| Allosteric Prediction | no (-0.642183076) |
| Ortholog in Animals | Alpaca_ HFM1 ( ortholog_one2one ) Dog_ HFM1 ( ortholog_one2one ) GuineaPig_ HFM1 ( ortholog_one2one ) Macaque_ HFM1 ( ortholog_one2one ) Mouse_ Hfm1 ( ortholog_one2one ) Pig_ HFM1 ( ortholog_one2one ) Rat_ Hfm1 ( ortholog_one2one ) Rabbit_ HFM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SKIV2L, SNRNP200, DDX60, DDX60L, HELQ, ASCC3, MTREX, POLQ |
| Tissue | testis |
| Tissue Specificity | Preferentially expressed in testis and ovary. {ECO:0000269|PubMed:17286053}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11165778 rs282009 rs587777269 rs587777268 rs11584478 |
| Subcellular location [CC] | NA |
| Mouse PG classification | HPG |
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