Gene Information
Gene NameHEY2
OrganismHomo sapiens (Human)
Gene Length337
Protein NamesHairy/enhancer-of-split related with YRPW motif protein 2 (Cardiovascular helix-loop-helix factor 1) (hCHF1) (Class B basic helix-loop-helix protein 32) (bHLHb32) (HES-related repressor protein 2) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HRT-2) (hHRT2) (Protein gridlock homolog)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000135547 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UBP5
Gene CardHEY2
Uniprot IDQ9UBP5
PfamPF07527; PF00010
In ASDno
Allosteric Predictionno (-0.46199884)
Ortholog in AnimalsAlpaca_ HEY2 ( ortholog_one2one )
Dog_ HEY2 ( ortholog_one2one )
GuineaPig_ HEY2 ( ortholog_one2one )
Macaque_ HEY2 ( ortholog_one2one )
Mouse_ Hey2 ( ortholog_one2one )
Pig_ HEY2 ( ortholog_one2one )
Rat_ Hey2 ( ortholog_one2one )
Rabbit_ HEY2 ( ortholog_one2one )
OhnologsHEY1, HEYL
ParalogsHEYL, BHLHE40, HES5, HES4, HES7, HES3, HEY1, HES2, HES1, HELT, HES6, BHLHE41
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.066667(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs747221103  rs3734638 
Subcellular location [CC]Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Mouse PG classificationNA
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