| Gene Information | |
|---|---|
| Gene Name | HEXA |
| Organism | Homo sapiens (Human) |
| Gene Length | 529 |
| Protein Names | Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000213614 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P06865 |
| Gene Card | HEXA |
| Uniprot ID | P06865 |
| Pfam | PF00728; PF14845 |
| In ASD | no |
| Allosteric Prediction | no (-0.348153835) |
| Ortholog in Animals | Alpaca_ HEXA ( ortholog_one2one ) Dog_ HEXA ( ortholog_one2one ) GuineaPig_ HEXA ( ortholog_one2one ) Macaque_ HEXA ( ortholog_one2one ) Mouse_ Hexa ( ortholog_one2one ) Pig_ HEXA ( ortholog_one2one ) Rat_ Hexa ( ortholog_one2one ) Rabbit_ HEXA ( ortholog_one2one ) |
| Ohnologs | HEXB |
| Paralogs | HEXB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GJX (X-ray 2.80A ) 2GK1 (X-ray 3.25A ) |
| DBSNP | rs121907979 rs748190164 rs121907975 rs121907957 rs121907972 rs121907953 rs28941770 rs28941770 rs28941771 rs387906310 rs753862880 rs121907973 rs1800429 rs121907976 rs121907961 rs121907974 rs769866128 rs121907970 rs138058578 rs121907959 rs1057521137 rs762255098 rs121907971 rs121907980 rs121907954 rs1054374 rs199578185 rs121907977 rs121907960 rs1555472696 rs797044434 rs772180415 rs772180415 rs1555472604 rs370266293 rs1800430 rs121907958 rs1800431 rs121907978 rs863225434 rs121907981 rs1057519467 rs121907952 rs121907968 rs121907966 rs121907956 rs28942071 rs121907955 |
| Subcellular location [CC] | Lysosome. |
| Mouse PG classification | NA |
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